The Trump administration's extreme cuts and restructuring at the Department of Health and Human Services are crippling America's leadership in biomedical research and putting millions of lives at risk. Critical research into cancer, Alzheimer's, diabetes and other diseases is being canceled as over 10,000 staff have been fired, including top vaccine official Peter Marks who resigned in protest of Secretary Kennedy's embrace of misinformation over facts. The paralysis at agencies like NIH is causing grant funding to slow dramatically, young researchers to have admission offers rescinded, and the next generation of scientific pioneers to be imperiled. From 2010 to 2019, NIH funding directly contributed to over 350 new drug approvals that have improved and saved countless lives. The U.S. cannot afford to surrender its global leadership in biomedical innovation. Robust funding for scientific research at NIH, universities and across the public and private sectors is vital to drive medical progress and maintain America's strategic advantage. Lawmakers must conduct vigorous oversight to stop the dismantling of HHS's scientific workforce and refocus these agencies on evidence-based policies that advance public health and biomedical breakthroughs, not fringe conspiracy theories. The future of cutting-edge treatments and cures for deadly diseases depends on it.